Estimating unmeasured anions in critically ill patients: Anion-gap, base-deficit, and strong-ion-gap

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Anion gap, anion gap corrected for albumin, base deficit and unmeasured anions in critically ill patients: implications on the assessment of metabolic acidosis and the diagnosis of hyperlactatemia

BACKGROUND Base deficit (BD), anion gap (AG), and albumin corrected anion gap (ACAG) are used by clinicians to assess the presence or absence of hyperlactatemia (HL). We set out to determine if these tools can diagnose the presence of HL using cotemporaneous samples. METHODS We conducted a chart review of ICU patients who had cotemporaneous arterial blood gas, serum chemistry, serum albumin (...

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Unmeasured anions and mortality in critically ill patients in 2016

The presence of acid-base disturbances, especially metabolic acidosis may negatively affect the outcome of critically ill patients. Lactic acidosis is the most frequent etiology and has largest impact on the prognosis. Since lactate measurement might not have always been available at bedside, it had been regarded as one of the unmeasured anions. Therefore, anion gap and strong ion gap has been ...

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Anion gap, anion gap corrected for albumin, and base deficit fail to accurately diagnose clinically significant hyperlactatemia in critically ill patients.

Anion gap, anion gap corrected for serum albumin, and base deficit are often used as surrogates for measuring serum lactate. None of these surrogates is postulated to predict hyperlactatemia in the critically ill. We prospectively collected data from September 2004 through August 2005 for 1381 consecutive admissions. Patients with renal disease, ketoacidosis, or toxic ingestion were excluded. A...

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The nature of unmeasured anions in critically ill patients

We read with interest the commentary of Venkatesh and Morgan in the February issue of Critical Care [1], in which they discuss the continuing need for clarification of the nature of unmeasured anions in critically ill patients. The questions asked in this commentary arise from the study of Bruegger and colleagues in a previous issue of this journal [2]. The main issue discussed is the ongoing u...

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Metabolic Acidosis and Strong Ion Gap in Critically Ill Patients with Acute Kidney Injury

PURPOSE To determine the influence of physicochemical parameters on survival in metabolic acidosis (MA) and acute kidney injury (AKI) patients. MATERIALS AND METHODS Seventy-eight MA patients were collected and assigned to AKI or non-AKI group. We analyzed the physiochemical parameters on survival at 24 h, 72 h, 1 week, 1 month, and 3 months after AKI. RESULTS Mortality rate was higher in t...

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ژورنال

عنوان ژورنال: Anaesthesia

سال: 2002

ISSN: 0003-2409

DOI: 10.1046/j.1365-2044.2002.02782_2.x